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[18] Quitting or reducing smoking has long-term health benefits, including longer life expectancy

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This, coupled with the more than 7,000 chemicals that are in each cigarette (at least 69 of which are cancer-causing) per the American Lung Association, makes smoking an extremely dangerous activity

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however, nephropathy was observed after dosing at 20 mg/kg/day for the same duration (approximately 0.2-times the highest recommended therapeutic dose based upon body surface area)